abstract：OBJECTIVE:To describe the influence of blood sampling/sampling tubes on mass spectrometric and clustering results, and on clinical blood variables, in blood samples collected from healthy volunteers and patients with prostate cancer. PATIENTS, SUBJECTS AND METHODS:Two venous blood samples were taken from 12 healthy vo...

journal_title：BJU international

authors： Pelzer AE,Feuerstein I,Fuchsberger C,Ongarello S,Bektic J,Schwentner C,Klocker H,Bartsch G,Bonn GK

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:To determine the feasibility of laparoscopic augmentation cystoplasty (LAC) in the porcine model and to compare LAC using standard bowel vs a small intestinal submucosa (SIS) allograft. MATERIALS AND METHODS:Fourteen female pigs underwent LAC; six had standard ileal AC and eight AC with SIS. All the pigs ha...

journal_title：BJU international

authors： Wang DS,Anderson DA,Fretz PC,Nguyen TT,Winfield HN

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To report our 12-year experience with radiological treatment (ureteric embolization) for refractory urinary fistula, as malignancy, radiation therapy, and/or chronic inflammation increase the risk of lower urinary tract fistula after surgical urinary diversion, which can lead to significant morbidity, and for...

journal_title：BJU international

authors： Shindel AW,Zhu H,Hovsepian DM,Brandes SB

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To explore patients' quality of life (QoL) during neoadjuvant hormone therapy (HT) using data from the Medical Research Council RT01 trial of standard- (64 Gy/32-fraction) and high- (74 Gy/37-fraction) dose radiotherapy (RT, both given conformally). PATIENTS AND METHODS:Of the 843 patients randomized to the ...

journal_title：BJU international

authors： Stephens RJ,Dearnaley DP,Cowan R,Sydes M,Naylor S,Fallowfield L,RT01 collaborators.

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To determine the long-term results of constructing a sigmoid neobladder after radical cystectomy for transitional cell carcinoma (TCC) of the urinary bladder. PATIENTS AND METHODS:The study included 170 patients with TCC of the bladder and a normal sigmoid colon. After radical cystectomy the neobladder was f...

journal_title：BJU international

authors： Yadav SS,Sadadukhi TC,Sharma KK,Yadav RG,Mathur R

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To describe patient selection for sacral neuromodulation, also known as Interstim therapy, and the results of tined-lead implantation in the medium term. PATIENTS AND METHODS:In all, 49 patients, 39 with refractory overactive bladder symptoms and 10 with urinary retention, were implanted with the tined lead ...

journal_title：BJU international

authors： Van Voskuilen AC,Oerlemans DJ,Weil EH,van den Hombergh U,van Kerrebroeck PE

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To report experience with a minimally invasive technique for palliation of urinary fistula/incontinence complicating advanced pelvic malignancy or its treatment. PATIENTS AND METHODS:We used ureteric embolization with permanent nephrostomy drainage in eight renal units in five patients for palliation of symp...

journal_title：BJU international

authors： Natarajan V,Boucher NR,Meiring P,Spencer P,Parys BT,Oakley NE,Stent (Society for Endourology in North Trent) Group.

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To investigate the validity of prostate-specific antigen (PSA) as a tumour marker in men with clinically localized prostate cancer who have selected watchful waiting, by determining if serial PSA level measurements are correlated with findings of malignancy or benign prostatic hyperplasia (BPH) at serial endo...

journal_title：BJU international

authors： Coakley FV,Chen I,Qayyum A,Westphalen AC,Carroll PR,Hricak H,Chen MH,Kurhanewicz J

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To determine the effects of cycling oestrogen in rabbits, as oestrogen is essential for physiological maintenance and integrity of the female urogenital tract. MATERIALS AND METHODS:Changes in circulating oestrogen have marked effects on the bladder of experimental animals, with ovariectomy (Ovx) inducing sm...

journal_title：BJU international

authors： Palmieri K,Mannikarottu AS,Chichester P,Kogan B,Leggett RE,Whitbeck C,Levin RM

更新日期：2007-01-01 00:00:00

abstract：:Data from the Japanese Urological Society showed that, in Japan, almost half of patients with localized prostate cancer are treated with hormone therapy (HT), regardless of disease stage, and that radiation therapy (RT) is also widely used to treat high-risk patients. A retrospective study was undertaken in Japan to e...

journal_title：BJU international

authors： Mizokami A,Ueno S,Fukagai T,Ito K,Ehara H,Kinbara H,Origasa H,Usami M,Namiki M,Akaza H

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of hypoxia-inducible factor-1alpha (HIF-1alpha) over-expression on the invasion-associated proteins in human prostate cancer cells, as HIF-1alpha is a transcriptional factor that could activate genes involved in the response to hypoxia, but might also enhance the invasive potency of pro...

journal_title：BJU international

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X,Zhau HE,Chung LW

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To retrospectively evaluate the efficacy and toxicity of chemotherapy with cisplatinum, methotrexate and bleomycin (CMB) in the adjuvant and palliative setting, and its effect on survival in patients with locally advanced or metastatic penile carcinoma, which carries a very poor prognosis. PATIENTS AND METHO...

journal_title：BJU international

authors： Hakenberg OW,Nippgen JB,Froehner M,Zastrow S,Wirth MP

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To compare changes in regional cerebral blood flow (rCBF), using positron emission tomography (PET), during chronic and acute sacral neuromodulation (SN). SN is an effective long-term treatment for chronic urge incontinence due to urinary bladder hyperactivity, as sensory nerves, spinal and supraspinal struct...

journal_title：BJU international

authors： Blok BF,Groen J,Bosch JL,Veltman DJ,Lammertsma AA

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of using urodynamic variables to predict upper urinary tract dilatation (UUTD) in children with neurogenic bladder-sphincter dysfunction (NBSD). PATIENTS AND METHODS:The study included 200 children with NBSD, of whom 103 had UUTD and 97 did not; they were examined using routine...

journal_title：BJU international

authors： Wang QW,Wen JG,Song DK,Su J,Che YY,Zhang P,Du AM,Wang DX,Zhu QH,Wei JX

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To explore the possibility that allogeneic responses might, by chance, encompass cross-reactive T cell clones specific for neo-antigenic tumour determinants, and thereby activate antitumour immunity; such cross-reactions are well documented for antiviral immunity, and genetic instability in developing cancers...

journal_title：BJU international

authors： Muir G,Rajbabu K,Callen C,Fabre JW

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To assess, in a retrospective study, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of digital rectal examination (DRE), transrectal ultrasonography (TRUS) and the combination of both in unilateral clinical T3a (cT3a) prostate cancer. PATIENTS AND METHODS:Th...

journal_title：BJU international

authors： Hsu CY,Joniau S,Oyen R,Roskams T,Van Poppel H

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To investigate the predictive value (PV) for all prostate cancers and for clinically significant cancer undiagnosed after a 10-core biopsy protocol, as the 10-core transrectal ultrasonography-guided biopsy is considered the standard technique of prostatic biopsy due to its high rate of detection of prostatic ...

journal_title：BJU international

authors： Park PC,Mai KT,Roustan Delatour NL,Morash C,Cagiannos I

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To investigate whether the antioxidant protection attributed to small heat-shock proteins (sHSPs) affects calcium oxalate stone formation, a pro-oxidant disease. MATERIALS AND METHODS:Canine distal tubular epithelial cells (Madin-Darby canine kidney, MDCK cells) were grown as confluent monolayers. Treatment ...

journal_title：BJU international

authors： Patel AB,Robertson WG,Choong S,Hothersall JS

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To assess the changing distribution of stage in seminoma and nonseminomatous germ cell tumours (NSGCTs), as recent reports contained no detailed information on pT stage and vascular invasion, important factors in the decision for further treatment. PATIENTS AND METHODS:Histopathological reports from 1976 to ...

journal_title：BJU international

authors： Lackner JE,Koller A,Mazal PR,Waldert M,Waldhoer T,Marberger M,Kratzik C

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To report the management of urachal anomalies using a robotically assisted approach. PATIENTS AND METHODS:Between January 2005 and February 2006, five patients (mean age 51 years, range 24-68) were diagnosed with urachal anomalies. Two basic robot-assisted surgical approaches were used for excising the urach...

journal_title：BJU international

authors： Madeb R,Knopf JK,Nicholson C,Donahue LA,Adcock B,Dever D,Tan BJ,Valvo JR,Eichel L

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:To determine the effects of LRIG1 on the growth, migration and invasion of bladder cancer cells and the mechanisms underlying such effects. MATERIALS AND METHODS:The plasmid pLRIG1-green fluorescence protein (GFP) was transfected into BIU87 bladder cancer cells by Lipofectamine2000 (Invitrogen, Groningen, t...

journal_title：BJU international

authors： Yang WM,Yan ZJ,Ye ZQ,Guo DS

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To evaluate ultrasensitive (US) measurements of prostate-specific antigen (PSA) level in men with prostate cancer, and to correlate the findings with currently accepted values for PSA recurrence, as PSA is widely accepted as a surrogate marker for disease recurrence after treatment for prostate cancer, and al...

journal_title：BJU international

authors： Taylor JA 3rd,Koff SG,Dauser DA,McLeod DG

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To describe the pattern and prevalence of lower urinary tract symptoms (LUTS) and related help-seeking behaviour in men of South Asian origin living in the UK, and to compare this to the white population. SUBJECTS AND METHODS:Data were obtained as part of the Leicestershire MRC Incontinence Study. Community-...

journal_title：BJU international

authors： Taylor J,McGrother CW,Harrison SC,Assassa PR,Leicestershire MRC Incontinence Study Team.

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To analyse the gene expression level of prostate stem cell antigen (PSCA) in human clear cell renal cell carcinoma (CC-RCC) and its relationship with conventional clinicopathological manifestations, to evaluate its prognostic value for patient outcome, and to determine the effect of PSCA on the progression o...

journal_title：BJU international

authors： Elsamman EM,Fukumori T,Tanimoto S,Nakanishi R,Takahashi M,Toida K,Kanayama HO

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the insertion of a urethral sling at the time of radical prostatectomy (RP) in men at high risk of urinary incontinence after RP. PATIENTS AND METHODS:Between 1998 and 2000, 49 of 871 men undergoing RP at The University of Texas M.D. Anderson Cancer Center, were identified as at risk of urinary i...

journal_title：BJU international

authors： Westney OL,Scott S,Wood C,Eddings T,Johnson MM,Taylor JM,McGuire E,Pisters LL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA). METHODS:A Medline search was conducted from January 1966 to June 2003 to identify human cli...

journal_title：BJU international

authors： Tulikangas PK,Ayers A,O'Sullivan DM

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of MN-001, a novel orally active anti-inflammatory agent, in suppressing the bladder hyperactivity resulting from ovalbumin (OA)-induced mast-cell stimulation in a rat model. MATERIALS AND METHODS:Sprague-Dawley rats of both sexes were divided into five groups of 10 each, with group 1...

journal_title：BJU international

authors： Rajasekaran M,Locke KW,Parsons CL

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To assess the severity of both stress urinary incontinence (SUI) and overactive bladder (OAB) symptoms during and after the first pregnancy, using a self-reported health-related quality-of-life questionnaire, and to assess the effect of pregnancy and childbirth on bothersome lower urinary tract symptoms (LUTS...

journal_title：BJU international

authors： van Brummen HJ,Bruinse HW,van de Pol G,Heintz AP,van der Vaart CH

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the accuracy of urethral ultrasonography (sono-urethrography, SUG) in determining the length of anterior urethral strictures, and for predicting the degree of spongiofibrosis. PATIENTS AND METHODS:In all, 52 patients with anterior urethral strictures detected on retrograde urethrography (RUG) wer...

journal_title：BJU international

authors： Gupta N,Dubey D,Mandhani A,Srivastava A,Kapoor R,Kumar A

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To examine differences in gene expression levels between renal cell carcinoma (RCC) tissue and 'normal' appearing renal tissue using a commercially available DNA macroarray. MATERIALS AND METHODS:Tissue was obtained from 47 consecutive radical nephrectomies, 29 of which were eligible. DNA macroarrays were an...

journal_title：BJU international

authors： Lovisolo JA,Casati B,Clerici L,Marafante E,Bono AV,Celato N,Salvadore M

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To investigate the impact of race on the effectiveness of hormonal therapy in patients with prostate cancer, by comparing the outcomes of Caucasian men (CM) and Japanese-American men (JAM) treated with hormonal therapy at one institution. PATIENTS AND METHODS:Fifty-nine CM and 105 JAM with prostate cancer we...

journal_title：BJU international

authors： Fukagai T,Namiki TS,Carlile RG,Yoshida H,Namiki M

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of using a tracer of 1% ethanol in 1.5% glycine for the early detection of irrigation fluid absorption during transurethral resection of the prostate (TURP). PATIENTS AND METHODS:In all, 126 men undergoing TURP were irrigated with a solution of 1% ethanol and 1.5% glycine; their expir...

journal_title：BJU international

authors： Collins JW,Macdermott S,Bradbrook RA,Keeley FX Jr,Timoney AG

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To analyse telomerase activity in disseminated prostate cancer cells isolated from bone marrow aspirates taken from men with localized prostate cancer before radical prostatectomy (RP). PATIENTS AND METHODS:Disseminated epithelial prostate cancer cells were isolated from bone marrow aspirates from 69 men wit...

journal_title：BJU international

authors： Pfitzenmaier J,Ellis WJ,Arfman EW,Hawley S,McLaughlin PO,Lange PH,Vessella RL

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To study the recovery of testosterone levels and erectile function in men who received radiotherapy plus long-term adjuvant androgen deprivation (LTAD) with luteinizing hormone-releasing hormone (LHRH) agonists. PATIENTS AND METHODS:From April 2000 to July 2001, men who had completed prostate radiotherapy wi...

journal_title：BJU international

authors： Wilke DR,Parker C,Andonowski A,Tsuji D,Catton C,Gospodarowicz M,Warde P

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To determine disease progression and survival in patients with lymph node-positive prostate carcinoma after ascending radical retropubic prostatectomy (RP) and pelvic lymphadenectomy with different forms of postoperative adjuvant treatment. PATIENTS AND METHODS:We analysed 82 patients with lymph node metasta...

journal_title：BJU international

authors： Kroepfl D,Loewen H,Roggenbuck U,Musch M,Klevecka V

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To investigate whether fluid shear stress (FSS) induces endothelial nitric oxide synthase (eNOS) activity and NO production in isolated human corpus cavernosal endothelial cells (HCCECs), and whether this response is altered during hyperglycaemia in vitro, as haemodynamic signalling during penile erection ind...

journal_title：BJU international

authors： Wessells H,Teal TH,Engel K,Sullivan CJ,Gallis B,Tran KB,Chitaley K

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To investigate the potential utility of a new combined immunostaining technique for diagnosing prostate cancer from histological analysis of needle biopsy specimens. MATERIALS AND METHODS:Tissue was immunostained with a combination of antibodies against a basal cell marker (p63), and an enzyme commonly overe...

journal_title：BJU international

authors： Molinié V,Hervé JM,Lugagne PM,Lebret T,Botto H

更新日期：2006-05-01 00:00:00

abstract：:There is ample evidence from many epidemiological studies that lower urinary tract symptoms (LUTS) and sexual dysfunction are strongly linked, independently of age and comorbidities such as hypertension, diabetes, dyslipidaemia and coronary heart disease. However, a causal link between both conditions is not yet estab...

journal_title：BJU international

authors： McVary K

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To assess the use of mitomycin C, by urologists within the UK, as a single-dose intravesical agent. Current European recommendations are to use one dose after any new tumour resection. METHODS:We assessed the current patterns of mitomycin C usage amongst British urologists, particularly with reference to one...

journal_title：BJU international

authors： Clarke NS,Basu S,Prescott S,Puri R

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To better understand the genital changes that occur during the female sexual response, using a gross anatomical and histological study of the vascular tissue of the vulva, supplemented with magnetic resonance imaging (MRI). MATERIALS AND METHODS:Seven cadaveric vulvectomy specimens were used; they were seria...

journal_title：BJU international

authors： Yang CC,Cold CJ,Yilmaz U,Maravilla KR

更新日期：2006-04-01 00:00:00